Genetics and characteristics
T gene belongs to a T-box gene family encoding transcription factors important during embryonic development. T gene mutation was first found in Pembroke Welsh Corgis and afterward in many other breeds. The mutation is dominantly inherited and results in a short-tail or tailless phenotype. Homozygosity for the mutation causes embryonic or postnatal lethality. Confirmation of the natural origin of a short tail is a necessity for breeders because an increased number of countries are prohibiting cutting tails.
Results Reported As
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References:
Hytönen, M.K., Grall, A., Hédan, B., Dréano, S., Seguin, S.J., Delattre, D., Thomas, A., Galibert, F., Paulin, L., Lohi, H., et al. (2009). Ancestral T-box mutation is present in many, but not all, short-tailed dog breeds. J. Hered. 100, 236–240.
Joanna Gruszczyńska, A.C. (2011). A molecular test for the detection of the C295G mutation in the T gene responsible for shortened tail and taillessness in the Pembroke Welsh Corgi. Annals of Warsaw University of Life Sciences – SGGW Land Reclamation 49, 35–43.